Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans

Calcineurin is the conserved target of the immunosuppressants cyclosporin A and FK506. Using the yeast two-hybrid system, we identified a novel calcineurin binding protein, CBP1, from the pathogenic fungus Cryptococcus neoformans. We show that CBP1 binds to calcineurin in vitro and in vivo, and FKBP...

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Hlavní autoři: Görlach, Jenifer, Fox, Deborah S., Cutler, N.Shane, Cox, Gary M., Perfect, John R., Heitman, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC313974/
https://ncbi.nlm.nih.gov/pubmed/10899116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3618
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