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Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans

Cryptococcus neoformans is a fungal pathogen that causes meningitis in immunocompromised patients. Its growth is sensitive to the immunosuppressants FK506 and cyclosporin, which inhibit the Ca(2+)– calmodulin-activated protein phosphatase calcineurin. Calcineurin is required for growth at 37°C and v...

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Bibliografiske detaljer
Main Authors: Cruz, M.Cristina, Fox, Deborah S., Heitman, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC145507/
https://ncbi.nlm.nih.gov/pubmed/11230126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.5.1020
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