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Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans
Cryptococcus neoformans is a fungal pathogen that causes meningitis in immunocompromised patients. Its growth is sensitive to the immunosuppressants FK506 and cyclosporin, which inhibit the Ca(2+)– calmodulin-activated protein phosphatase calcineurin. Calcineurin is required for growth at 37°C and v...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC145507/ https://ncbi.nlm.nih.gov/pubmed/11230126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.5.1020 |
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