Possible association of BLM in decreasing DNA double strand breaks during DNA replication

Bloom’s syndrome (BS) is a rare genetic disorder and the cells from BS patients show genomic instability and an increased level of sister chromatid exchange (SCE). We generated BLM(–/–) and BLM(–/–)/RAD54(–/–) DT40 cells from the chicken B-lymphocyte line DT40. The BLM(–/–) DT40 cells showed higher...

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Hoofdauteurs: Wang, Wensheng, Seki, Masayuki, Narita, Yoshiyasu, Sonoda, Eiichiro, Takeda, Shunichi, Yamada, Kouichi, Masuko, Takashi, Katada, Toshiaki, Enomoto, Takemi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC313960/
https://ncbi.nlm.nih.gov/pubmed/10880455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3428
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