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Genetic Variants of the ENPP1/PC-1 Gene Are Associated With Hypertriglyceridemia in Male Subjects

BACKGROUND: Hypertriglyceridemia is associated with insulin resistance, type 2 diabetes, and the metabolic syndrome. Membrane glycoprotein PC-1 (also termed ENPP1) is a direct insulin receptor inhibitor, and certain polymorphisms of the ENPP1/PC-1 gene have been associated with insulin resistance, t...

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Detalhes bibliográficos
Main Authors: Tanyolaç, Sinan, Bremer, Andrew A., Hodoglugil, Uǧur, Movsesyan, Irina, Pullinger, Clive R., Heiner, Steven W., Malloy, Mary J., Kane, John P., Goldfine, Ira D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. publishers 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139525/
https://ncbi.nlm.nih.gov/pubmed/19656007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/met.2009.0027
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