An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients

Apolipoprotein A-V (apoA-V) is an important regulator of plasma levels of triglyceride (TG) in mice. In humans, APOA5 genetic variation is associated with TG in several populations. In this study, we determined the effects of the p.185Gly>Cys (c.553G>T; rs2075291) polymorphism on plasma TG lev...

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Autors principals: Pullinger, Clive R., Aouizerat, Bradley E., Movsesyan, Irina, Durlach, Vincent, Sijbrands, Eric J., Nakajima, Katsuyuki, Poon, Annie, Dallinga-Thie, Geesje M., Hattori, Hiroaki, Green, Lauri L., Kwok, Pui-Yan, Havel, Richard J., Frost, Philip H., Malloy, Mary J., Kane, John P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Patient-Oriented and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2444008/
https://ncbi.nlm.nih.gov/pubmed/18441017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P800011-JLR200
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