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Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals

Vulval induction in Caenorhabditis elegans has helped define an evolutionarily conserved signal transduction pathway from receptor tyrosine kinases (RTKs) through the adaptor protein SEM-5 to RAS. One component present in other organisms, a guanine nucleotide exchange factor for Ras, has been missin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chang, Chieh, Hopper, Neil A., Sternberg, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC313952/
https://ncbi.nlm.nih.gov/pubmed/10880441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3283
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