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Requirements of Multiple Domains of SLI-1, a Caenorhabditis elegans Homologue of c-Cbl, and an Inhibitory Tyrosine in LET-23 in Regulating Vulval Differentiation

SLI-1, a Caenorhabditis elegans homologue of the proto-oncogene product c-Cbl, is a negative regulator of LET-23-mediated vulval differentiation. Lack of SLI-1 activity can compensate for decreased function of the LET-23 epidermal growth factor receptor, the SEM-5 adaptor, but not the LET-60 RAS, su...

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Bibliographische Detailangaben
Hauptverfasser: Yoon, Charles H., Chang, Chieh, Hopper, Neil A., Lesa, Giovanni M., Sternberg, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15054/
https://ncbi.nlm.nih.gov/pubmed/11071924
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