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Requirements of Multiple Domains of SLI-1, a Caenorhabditis elegans Homologue of c-Cbl, and an Inhibitory Tyrosine in LET-23 in Regulating Vulval Differentiation

SLI-1, a Caenorhabditis elegans homologue of the proto-oncogene product c-Cbl, is a negative regulator of LET-23-mediated vulval differentiation. Lack of SLI-1 activity can compensate for decreased function of the LET-23 epidermal growth factor receptor, the SEM-5 adaptor, but not the LET-60 RAS, su...

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Publicat a:Mol Biol Cell
Autors principals: Yoon, Charles H., Chang, Chieh, Hopper, Neil A., Lesa, Giovanni M., Sternberg, Paul W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11071924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.11.11.4019
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