Phase II Study of Aflibercept in Recurrent Malignant Glioma: A North American Brain Tumor Consortium Study

PURPOSE: Antivascular endothelial growth factor (anti-VEGF) therapy is a promising treatment approach for patients with recurrent glioblastoma. This single-arm phase II study evaluated the efficacy of aflibercept (VEGF Trap), a recombinantly produced fusion protein that scavenges both VEGF and place...

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Main Authors: de Groot, John F., Lamborn, Kathleen R., Chang, Susan M., Gilbert, Mark R., Cloughesy, Timothy F., Aldape, Kenneth, Yao, Jun, Jackson, Edward F., Lieberman, Frank, Robins, H. Ian, Mehta, Minesh P., Lassman, Andrew B., DeAngelis, Lisa M., Yung, W.K. Alfred, Chen, Alice, Prados, Michael D., Wen, Patrick Y.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2011
Teme:
Original Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139373/
https://ncbi.nlm.nih.gov/pubmed/21606416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.34.1636
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