Nalaganje...

A ring-opening mechanism for DNA binding in the central channel of the T7 helicase–primase protein

We have investigated the mechanism of binding single-stranded DNA (ssDNA) into the central channel of the ring-shaped T7 gp4A′ helicase–primase hexamer. Presteady-state kinetic studies show a facilitated five-step mechanism and provide understanding of how a ring-shaped helicase can be loaded on the...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ahnert, Peter, Picha, Kristen Moore, Patel, Smita S.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC313936/
https://ncbi.nlm.nih.gov/pubmed/10880454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3418
Oznake: Označite
Brez oznak, prvi označite!