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Distinct patterns of activation-dependent changes in conformational mobility between ERK1 and ERK2
Hydrogen/deuterium exchange measurements by mass spectrometry (HX-MS) can be used to report localized conformational mobility within folded proteins, where exchange predominantly occurs through low energy fluctuations in structure, allowing transient solvent exposure. Changes in conformational mobil...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139246/ https://ncbi.nlm.nih.gov/pubmed/21785572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijms.2010.08.020 |
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