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Hyaluronan Oligosaccharides Induce Matrix Metalloproteinase 13 via Transcriptional Activation of NFκB and p38 MAP Kinase in Articular Chondrocytes

Hyaluronan exerts a variety of biological effects on cells including changes in cell migration, proliferation, and matrix metabolism. However, the signaling pathways associated with the action of hyaluronan on cells have not been clearly defined. In some cells, signaling is induced by the loss of ce...

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Autors principals: Ohno, Shigeru, Im, Hee-Jeong, Knudson, Cheryl B., Knudson, Warren
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139229/
https://ncbi.nlm.nih.gov/pubmed/16648633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M602750200
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