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T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway
Latent HIV proviruses are thought to be primarily reactivated in vivo through stimulation of the T-cell receptor (TCR). Activation of the T-cell receptor (TCR) induces multiple signal transduction pathways leading to the ordered nuclear migration of the HIV transcription initiation factors NF-κB and...
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Autori principali: | , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139146/ https://ncbi.nlm.nih.gov/pubmed/21763495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.054 |
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