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T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway

Latent HIV proviruses are thought to be primarily reactivated in vivo through stimulation of the T-cell receptor (TCR). Activation of the T-cell receptor (TCR) induces multiple signal transduction pathways leading to the ordered nuclear migration of the HIV transcription initiation factors NF-κB and...

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Autori principali: Kim, Young Kyeung, Mbonye, Uri, Hokello, Joseph, Karn, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139146/
https://ncbi.nlm.nih.gov/pubmed/21763495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.03.054
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