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Transcriptional control of HIV latency: Cellular signaling pathways, epigenetics, happenstance and the hope for a cure
Replication-competent latent HIV-1 proviruses that persist in the genomes of a very small subset of resting memory T cells in infected individuals under life-long antiretroviral therapy present a major barrier towards viral eradication. Multiple molecular mechanisms are required to repress the viral...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010583/ https://ncbi.nlm.nih.gov/pubmed/24565118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.02.008 |
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