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Sprouty2 Regulates PI(4,5)P(2)/Ca(2+) Signaling and HIV-1 Gag Release
We recently reported that activation of the inositol 1,4,5-triphosphate receptor (IP3R) is required for efficient HIV-1 Gag trafficking and viral particle release (Ehrlich 2010). IP3R activation requires phospholipase C (PLC)-catalyzed hydrolysis of PI(4,5)P(2) to IP3 and diacylglycerol. Here we sho...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139110/ https://ncbi.nlm.nih.gov/pubmed/21762810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.069 |
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