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ESCRT Machinery Potentiates HIV-1 Utilization of the PI(4,5)P(2)-PLC-IP3R-Ca(2+) Signaling Cascade
HIV-1 release efficiency is directed by late (L) domain motifs in the viral structural precursor polyprotein, Gag, which serve as links to the ESCRT (endocytic sorting complex required for transport) machinery. Linkage is normally through binding of Tsg101, an ESCRT-1 component, to the P(7)TAP motif...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193579/ https://ncbi.nlm.nih.gov/pubmed/21875593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.08.038 |
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