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ESCRT Machinery Potentiates HIV-1 Utilization of the PI(4,5)P(2)-PLC-IP3R-Ca(2+) Signaling Cascade

HIV-1 release efficiency is directed by late (L) domain motifs in the viral structural precursor polyprotein, Gag, which serve as links to the ESCRT (endocytic sorting complex required for transport) machinery. Linkage is normally through binding of Tsg101, an ESCRT-1 component, to the P(7)TAP motif...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ehrlich, Lorna S., Medina, Gisselle N., Carter, Carol A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193579/
https://ncbi.nlm.nih.gov/pubmed/21875593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.08.038
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