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Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11
CYP102A1, originating from Bacillus megaterium, is a highly active enzyme which has attracted much attention because of its potential applicability as a biocatalyst for oxidative reactions. Previously we developed drug-metabolizing mutant CYP102A1 M11 by a combination of site-directed and random mut...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Springer-Verlag
2011
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3139092/ https://ncbi.nlm.nih.gov/pubmed/21567268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-011-0789-4 |
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