Different Patterns of Expansion, Contraction and Memory Differentiation of HIV-1 Gag-Specific CD8 T Cells Elicited by Adenovirus Type 5 and Modified Vaccinia Ankara Vaccines

The magnitude and functional quality of antiviral CD8 T cell responses are critical for the efficacy of T cell based vaccines. Here, we investigate the influence of two popular viral vectors, adenovirus type 5 (Ad5) and modified vaccinia Ankara (MVA), on expansion, contraction and memory differentia...

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Detalhes bibliográficos
Main Authors: Pillai, Vinod Kumar Bhaskara, Kannanganat, Sunil, Penaloza-MacMaster, Pablo, Chennareddi, Lakshmi, Robinson, Harriet L., Blackwell, Jerry, Amara, Rama Rao
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139022/
https://ncbi.nlm.nih.gov/pubmed/21651938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.05.083
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