Single Intra-Articular Injection of Adeno-Associated Virus Results in Stable and Controllable In vivo Transgene Expression in Normal Rat Knees

OBJECTIVE: To test the hypothesis that in vivo transgene expression mediated by single intra-articular injection of adeno-associated virus serotype 2 (AAV2) persists within intra-articular tissues 1-year post-injection and can be externally controlled using an AAV2-based tetracycline-inducible gene...

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Bibliographic Details
Main Authors: Payne, Karin A., Lee, Hannah H., Haleem, Amgad M., Martins, Cesar, Yuan, Zhenhua, Qiao, Chunping, Xiao, Xiao, Chu, Constance R.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139006/
https://ncbi.nlm.nih.gov/pubmed/21571082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2011.04.009
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