Llwytho...

Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors

Aberrant forms of the anaplastic lymphoma kinase (ALK) have been implicated in the pathogenesis of multiple human cancers, where ALK represents a rational therapeutic target in these settings. In this study, we report the identification and biological characterization of X-376 and X-396, two potent...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lovly, Christine M., Heuckmann, Johannes M., de Stanchina, Elisa, Chen, Heidi, Thomas, Roman K., Liang, Chris, Pao, William
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138877/
https://ncbi.nlm.nih.gov/pubmed/21613408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3879
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