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A Small Peptide Modeled after the NRAGE Repeat Domain Inhibits XIAP-TAB1-TAK1 Signaling for NF-κB Activation and Apoptosis in P19 Cells

In normal growth and development, apoptosis is necessary to shape the central nervous system and to eliminate excess neurons which are not required for innervation. In some diseases, however, apoptosis can be either overactive as in some neurodegenerative disorders or severely attenuated as in the s...

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Главные авторы: Rochira, Jennifer A., Matluk, Nicholas N., Adams, Tamara L., Karaczyn, Aldona A., Oxburgh, Leif, Hess, Samuel T., Verdi, Joseph M.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138748/
https://ncbi.nlm.nih.gov/pubmed/21789165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020659
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