تحميل...
Abrogation of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and separation of GVHD from GVL
IL-21 is a proinflammatory cytokine produced by Th17 cells. Abrogation of IL-21 signaling has recently been shown to reduce GVHD while retaining graft-versus-leukemia/lymphoma (GVL) responses. However, the mechanisms by which IL-21 may lead to a separation of GVHD and GVL remain incompletely underst...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society of Hematology
2011
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138694/ https://ncbi.nlm.nih.gov/pubmed/21596854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-07-294785 |
| الوسوم: |
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