Folate Intake, Mthfr Genotype, and Sex Modulate Choline Metabolism in Mice(2)

Choline and folate are interrelated in 1-carbon metabolism, mostly because of their shared function as methyl donors for homocysteine remethylation. Folate deficiency and mutations of methylenetetrahydrofolate reductase (MTHFR) reduce the availability of a major methyl donor, 5-methyltetrahydrofolat...

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Main Authors: Chew, Tina W., Jiang, Xinyin, Yan, Jian, Wang, Wei, Lusa, Amanda L., Carrier, Bradley J., West, Allyson A., Malysheva, Olga V., Brenna, J. Thomas, Gregory, Jesse F., Caudill, Marie A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Nutrition 2011
Assuntos:
Nutrient Requirements and Optimal Nutrition
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138639/
https://ncbi.nlm.nih.gov/pubmed/21697299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.111.138859
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