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Polymerase ribozyme efficiency increased by G/T-rich DNA oligonucleotides

The RNA world hypothesis states that the early evolution of life went through a stage where RNA served as genome and as catalyst. The replication of RNA world organisms would have been facilitated by ribozymes that catalyze RNA polymerization. To recapitulate an RNA world in the laboratory, a series...

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Bibliographic Details
Main Authors: Yao, Chengguo, Müller, Ulrich F.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138564/
https://ncbi.nlm.nih.gov/pubmed/21622900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2726811
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