IUGR DECREASES PPARγ AND SETD8 EXPRESSION IN NEONATAL RAT LUNG AND THESE EFFECTS ARE AMELIORATED BY MATERNAL DHA SUPPLEMENTATION

Intrauterine growth restriction (IUGR) is associated with altered lung development in human and rat. The transcription factor PPARγ, is thought to contribute to lung development. PPARγ is activated by docosahexanoic acid (DHA). One contribution of PPARγ to lung development may be its direct regulati...

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Hauptverfasser: Joss-Moore, Lisa A., Wang, Yan, Baack, Michelle L., Yao, Jianrong, Norris, Andrew W., Yu, Xing, Callaway, Christopher W., McKnight, Robert A., Albertine, Kurt H., Lane, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138525/
https://ncbi.nlm.nih.gov/pubmed/20869820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.earlhumdev.2010.08.026
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