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Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion

Host cyclophilin (cyp) inhibitors, such as NIM811, efficiently inhibit replication of hepatitis C virus (HCV) and have shown significant promise in recent clinical trials for the treatment of chronic HCV. It is therefore important to fully understand the mechanism of action of these therapeutic agen...

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Hlavní autoři: Anderson, Leah J, Lin, Kai, Compton, Teresa, Wiedmann, Brigitte
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138436/
https://ncbi.nlm.nih.gov/pubmed/21711559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-329
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