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Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif

BACKGROUND: The interactions between PDZ (PSD-95, Dlg, ZO-1) domains and PDZ-binding motifs play central roles in signal transductions within cells. Proteins with PDZ domains bind to PDZ-binding motifs almost exclusively when the motifs are located at the carboxyl (C-) terminal ends of their binding...

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Autors principals: Chimura, Takahiko, Launey, Thomas, Ito, Masao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138430/
https://ncbi.nlm.nih.gov/pubmed/21649932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-300
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