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Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6

Toll-like receptors (TLRs) modulate the expression of multiple microRNAs (miRNAs). Here, we report the down-regulation of miR-107 by TLR4 in multiple cell types. The miR-107 sequence occurs in an intron within the sequence encoding the gene for pantothenate kinase 1α (PanK1α), which is regulated by...

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Detalhes bibliográficos
Main Authors: Hennessy, Elizabeth J., Sheedy, Frederick J., Santamaria, David, Barbacid, Mariano, O'Neill, Luke A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138295/
https://ncbi.nlm.nih.gov/pubmed/21628465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256206
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