ZPK/DLK, a Mitogen-Activated Protein Kinase Kinase Kinase, Is a Critical Mediator of Programmed Cell Death of Motoneurons

Activation of mitogen-activated protein kinase pathways is critically involved in naturally occurring programmed cell death of motoneurons during development, but the upstream mediators remain undetermined. We found that mice deficient in ZPK, also called DLK (ZPK/DLK), an upstream kinase in these p...

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Bibliographic Details
Main Authors: Itoh, Aki, Horiuchi, Makoto, Wakayama, Kouji, Xu, Jie, Bannerman, Peter, Pleasure, David, Itoh, Takayuki
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2011
Subjects:
Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138193/
https://ncbi.nlm.nih.gov/pubmed/21593306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5947-10.2011
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