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Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling
Drosophila epithelia acquire a planar cell polarity (PCP) orthogonal to their apical-basal axes. Frizzled (Fz) is the receptor for the PCP signal, and Dishevelled (Dsh) transduces the signal. Here, I demonstrate that unipolar relocalization of Dsh to the membrane is required to mediate PCP, but not...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory Press
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313798/ https://ncbi.nlm.nih.gov/pubmed/11358862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.890501 |
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