Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization

Dishevelled (Dsh) is a cytoplasmic multidomain protein that is required for all known branches of the Wnt signalling pathway1–3. The Frizzled/planar cell polarity (Fz/PCP) signalling branch requires an asymmetric cortical localization of Dsh, but this process remains poorly understood. Using a genom...

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Hlavní autoři: Simons, Matias, Gault, William J., Gotthardt, Daniel, Rohatgi, Rajeev, Klein, Thomas J., Shao, Youming, Lee, Ho-Jin, Wu, Ai-Luen, Fang, Yimin, Satlin, Lisa M., Dow, Julian T., Chen, Jie, Zheng, Jie, Boutros, Michael, Mlodzik, Marek
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803043/
https://ncbi.nlm.nih.gov/pubmed/19234454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1836
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