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High-throughput RNAi screening identifies a role for TNK1 in growth and survival of pancreatic cancer cells

In order to identify novel targets in pancreatic cancer cells, we utilized high-throughput RNAi (HT-RNAi) to identify genes that, when silenced, would decrease viability of pancreatic cancer cells. The HT-RNAi screen involved reverse transfecting the pancreatic cancer cell line BxPC3 with a siRNA li...

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Библиографические подробности
Главные авторы: Henderson, Meredith C., Gonzales, Irma M., Arora, Shilpi, Choudhary, Ashish, Trent, Jeffrey M., Von Hoff, Daniel D., Mousses, Spyro, Azorsa, David O.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137903/
https://ncbi.nlm.nih.gov/pubmed/21536687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0436
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