Effects of cell-type specific leptin receptor mutation on leptin transport across the BBB

The functions of leptin receptors (LRs) are cell-type specific. At the blood-brain barrier, LRs mediate leptin transport that is essential for its CNS actions, and both endothelial and astrocytic LRs may be involved. To test this, we generated endothelia specific LR knockout (ELKO) and astrocyte spe...

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Detalhes bibliográficos
Main Authors: Hsuchou, Hung, Kastin, Abba J., Tu, Hong, Markadakis, Emily N., Stone, Kirsten P., Wang, Yuping, Heymsfield, Steven B., Chua, Streamson S., Obici, Silvana, Magrisso, I. Jack, Pan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137692/
https://ncbi.nlm.nih.gov/pubmed/21616110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2011.05.011
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