Agaricus blazei Extract Induces Apoptosis through ROS-Dependent JNK Activation Involving the Mitochondrial Pathway and Suppression of Constitutive NF-κB in THP-1 Cells

Agaricus blazei is widely accepted as a traditional medicinal mushroom, and it has been known to exhibit immunostimulatory and anti-cancer activity. However, the apoptotic mechanism in cancer cells is poorly understood. In this study, we have investigated whether A. blazei extract (ABE) exerts antip...

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Bibliographic Details
Main Authors: Kim, Mun-Ock, Moon, Dong-Oh, Jung, Jin Myung, Lee, Won Sup, Choi, Yung Hyun, Kim, Gi-Young
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137680/
https://ncbi.nlm.nih.gov/pubmed/19861509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecam/nep176
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