Activation of Protein Kinase C Delta following Cerebral Ischemia Leads to Release of Cytochrome C from the Mitochondria via Bad Pathway

BACKGROUND: The release of cytochrome c from the mitochondria following cerebral ischemia is a key event leading to cell death. The goal of the present study was to determine the mechanisms involved in post-ischemic activation of protein kinase c delta (δPKC) that lead to cytochrome c release. METHO...

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Detalhes bibliográficos
Main Authors: Dave, Kunjan R., Bhattacharya, Sanjoy K., Saul, Isabel, DeFazio, R. Anthony, Dezfulian, Cameron, Lin, Hung Wen, Raval, Ami P., Perez-Pinzon, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137627/
https://ncbi.nlm.nih.gov/pubmed/21789211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022057
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