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The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits

The integrated analysis of genotypic and expression data for association with complex traits could identify novel genetic pathways involved in complex traits. We profiled 19,573 expression probes in Epstein-Barr virus-transformed lymphoblastoid cell lines (LCLs) from 299 twins and correlated these w...

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Bibliographische Detailangaben
Hauptverfasser: Min, Josine L., Taylor, Jennifer M., Richards, J. Brent, Watts, Tim, Pettersson, Fredrik H., Broxholme, John, Ahmadi, Kourosh R., Surdulescu, Gabriela L., Lowy, Ernesto, Gieger, Christian, Newton-Cheh, Chris, Perola, Markus, Soranzo, Nicole, Surakka, Ida, Lindgren, Cecilia M., Ragoussis, Jiannis, Morris, Andrew P., Cardon, Lon R., Spector, Tim D., Zondervan, Krina T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137612/
https://ncbi.nlm.nih.gov/pubmed/21789213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022070
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