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The Use of Genome-Wide eQTL Associations in Lymphoblastoid Cell Lines to Identify Novel Genetic Pathways Involved in Complex Traits

The integrated analysis of genotypic and expression data for association with complex traits could identify novel genetic pathways involved in complex traits. We profiled 19,573 expression probes in Epstein-Barr virus-transformed lymphoblastoid cell lines (LCLs) from 299 twins and correlated these w...

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Hlavní autoři: Min, Josine L., Taylor, Jennifer M., Richards, J. Brent, Watts, Tim, Pettersson, Fredrik H., Broxholme, John, Ahmadi, Kourosh R., Surdulescu, Gabriela L., Lowy, Ernesto, Gieger, Christian, Newton-Cheh, Chris, Perola, Markus, Soranzo, Nicole, Surakka, Ida, Lindgren, Cecilia M., Ragoussis, Jiannis, Morris, Andrew P., Cardon, Lon R., Spector, Tim D., Zondervan, Krina T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137612/
https://ncbi.nlm.nih.gov/pubmed/21789213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022070
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