Gene Expression in Skin and Lymphoblastoid Cells: Refined Statistical Method Reveals Extensive Overlap in cis-eQTL Signals

Psoriasis, an immune-mediated, inflammatory disease of the skin and joints, provides an ideal system for expression quantitative trait locus (eQTL) analysis, because it has a strong genetic basis and disease-relevant tissue (skin) is readily accessible. To better understand the role of genetic varia...

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Main Authors: Ding, Jun, Gudjonsson, Johann E., Liang, Liming, Stuart, Philip E., Li, Yun, Chen, Wei, Weichenthal, Michael, Ellinghaus, Eva, Franke, Andre, Cookson, William, Nair, Rajan P., Elder, James T., Abecasis, Gonçalo R.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997368/
https://ncbi.nlm.nih.gov/pubmed/21129726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.10.024
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