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Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation

Myostatin (MSTN) is a member of the transforming growth factor-β superfamily of cytokines and is a negative regulator of skeletal muscle mass. Compared with MSTN(+/+) mice, the extensor digitorum longus muscles of MSTN(−/−) mice exhibit hypertrophy, hyperplasia, and greater maximum isometric force p...

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Autors principals: Mendias, Christopher L., Kayupov, Erdan, Bradley, Joshua R., Brooks, Susan V., Claflin, Dennis R.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137541/
https://ncbi.nlm.nih.gov/pubmed/21565991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00126.2011
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