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Intrinsic stiffness of extracellular matrix increases with age in skeletal muscles of mice

Advanced age is associated with increases in muscle passive stiffness, but the contributors to the changes remain unclear. Our purpose was to determine the relative contributions of muscle fibers and extracellular matrix (ECM) to muscle passive stiffness in both adult and old animals. Passive mechan...

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Main Authors: Wood, Lauren K., Kayupov, Erdan, Gumucio, Jonathan P., Mendias, Christopher L., Claflin, Dennis R., Brooks, Susan V.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137235/
https://ncbi.nlm.nih.gov/pubmed/24994884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00256.2014
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