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Attenuation of muscle atrophy by an N-terminal peptide of the receptor for proteolysis-inducing factor (PIF)

BACKGROUND: Atrophy of skeletal muscle in cancer cachexia has been attributed to a tumour-produced highly glycosylated peptide called proteolysis-inducing factor (PIF). The action of PIF is mediated through a high-affinity membrane receptor in muscle. This study investigates the ability of peptides...

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Autori principali: Mirza, K A, Wyke, S M, Tisdale, M J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137423/
https://ncbi.nlm.nih.gov/pubmed/21673682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.216
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