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AhR deficiency impairs expression of LPS-induced inflammatory genes in mice

Recent reports suggest the participation of the aryl hydrocarbon receptor (AhR) in the induction mechanism of the NF-κB signaling pathway. In the current study we challenged C57BL/6 wild-type (WT) and AhR deficient (AhR(−/−)) mice with bacterial lipopolysaccharide (LPS) to investigate the role of th...

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Autori principali: Wu, Dalei, Li, Wen, Lok, Patty, Matsumura, Fumio, Vogel, Christoph Franz Adam
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137281/
https://ncbi.nlm.nih.gov/pubmed/21683686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.06.018
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