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A probabilistic method for the detection and genotyping of small indels from population-scale sequence data

Motivation: High-throughput sequencing technologies have made population-scale studies of human genetic variation possible. Accurate and comprehensive detection of DNA sequence variants is crucial for the success of these studies. Small insertions and deletions represent the second most frequent cla...

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Main Authors: Bansal, Vikas, Libiger, Ondrej
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137221/
https://ncbi.nlm.nih.gov/pubmed/21653520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr344
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