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Parent-specific copy number in paired tumor–normal studies using circular binary segmentation

Motivation: High-throughput techniques facilitate the simultaneous measurement of DNA copy number at hundreds of thousands of sites on a genome. Older techniques allow measurement only of total copy number, the sum of the copy number contributions from the two parental chromosomes. Newer single nucl...

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Bibliografske podrobnosti
Main Authors: Olshen, Adam B., Bengtsson, Henrik, Neuvial, Pierre, Spellman, Paul T., Olshen, Richard A., Seshan, Venkatraman E.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137217/
https://ncbi.nlm.nih.gov/pubmed/21666266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr329
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