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Parent-specific copy number in paired tumor–normal studies using circular binary segmentation
Motivation: High-throughput techniques facilitate the simultaneous measurement of DNA copy number at hundreds of thousands of sites on a genome. Older techniques allow measurement only of total copy number, the sum of the copy number contributions from the two parental chromosomes. Newer single nucl...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Oxford University Press
2011
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Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137217/ https://ncbi.nlm.nih.gov/pubmed/21666266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btr329 |
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