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Bioinformatic Prediction and Confirmation of β-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

It is important to identify the true substrates of protein kinases because this illuminates the primary function of any kinase. Here, we used bioinformatics and biochemical validation to identify novel brain substrates of the Ser/Thr kinase glycogen synthase kinase 3 (GSK3). Briefly, sequence databa...

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Detalles Bibliográficos
Autores principales: Farghaian, Hovik, Turnley, Ann M., Sutherland, Calum, Cole, Adam R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137098/
https://ncbi.nlm.nih.gov/pubmed/21606488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251629
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