Distinct Priming Kinases Contribute to Differential Regulation of Collapsin Response Mediator Proteins by Glycogen Synthase Kinase-3 in Vivo

Collapsin response mediator proteins (CRMPs) are a family of neuron-enriched proteins that regulate neurite outgrowth and growth cone dynamics. Here, we show that Cdk5 phosphorylates CRMP1, CRMP2, and CRMP4, priming for subsequent phosphorylation by GSK3 in vitro. In contrast, DYRK2 phosphorylates a...

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Detalhes bibliográficos
Main Authors: Cole, Adam R., Causeret, Frédéric, Yadirgi, Gokhan, Hastie, C. James, McLauchlan, Hilary, McManus, Edward J., Hernández, Félix, Eickholt, Britta J., Nikolic, Margareta, Sutherland, Calum
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805471/
https://ncbi.nlm.nih.gov/pubmed/16611631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M513344200
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