Luminal Lipid Regulates CD36 Levels and Downstream Signaling to Stimulate Chylomicron Synthesis

The membrane glycoprotein CD36 binds nanomolar concentrations of long chain fatty acids (LCFA) and is highly expressed on the luminal surface of enterocytes. CD36 deficiency reduces chylomicron production through unknown mechanisms. In this report, we provide novel insights into some of the underlyi...

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Autors principals: Tran, Thi Thu Trang, Poirier, Hélène, Clément, Lionel, Nassir, Fatiha, Pelsers, Maurice M. A. L., Petit, Valérie, Degrace, Pascal, Monnot, Marie-Claude, Glatz, Jan F. C., Abumrad, Nada A., Besnard, Philippe, Niot, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137091/
https://ncbi.nlm.nih.gov/pubmed/21610069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233551
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