Luminal Lipid Regulates CD36 Levels and Downstream Signaling to Stimulate Chylomicron Synthesis

The membrane glycoprotein CD36 binds nanomolar concentrations of long chain fatty acids (LCFA) and is highly expressed on the luminal surface of enterocytes. CD36 deficiency reduces chylomicron production through unknown mechanisms. In this report, we provide novel insights into some of the underlyi...

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Bibliografiska uppgifter
Huvudupphovsmän: Tran, Thi Thu Trang, Poirier, Hélène, Clément, Lionel, Nassir, Fatiha, Pelsers, Maurice M. A. L., Petit, Valérie, Degrace, Pascal, Monnot, Marie-Claude, Glatz, Jan F. C., Abumrad, Nada A., Besnard, Philippe, Niot, Isabelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Metabolism
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137091/
https://ncbi.nlm.nih.gov/pubmed/21610069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233551
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