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Antibody Recognition of a Human Chorionic Gonadotropin Epitope (hCGβ(66–80)) Depends on Local Structure Retained in the Free Peptide

Human chorionic gonadotropin (hCG) is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays. Intelligent epitope selection is essential to achieving the required assay performance. We present binding affinity measurements demonstrati...

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Autors principals: Gregor, Craig R., Cerasoli, Eleonora, Schouten, James, Ravi, Jascindra, Slootstra, Jerry, Horgan, Adrian, Martyna, Glenn J., Ryadnov, Maxim G., Davis, Paul, Crain, Jason
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137075/
https://ncbi.nlm.nih.gov/pubmed/21592960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246637
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